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Neutrogena® Rapid Wrinkle Repair Regenerating Cream 48g

Neutrogena® Rapid Wrinkle Repair Regenerating Cream 48g is rated 3.8 out of 5 by 906.
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This rich moisturising cream delivers our highest concentration of Accelerated Retinol SA to the skin’s surface quickly and effectively, for visibly smoother and younger-looking skin in just one week.

Clinically proven to:

  • Fade the look of coarse deep wrinkles, including crow’s feet, forehead and cheek wrinkles
  • Regenerate the look of skin
  • Smooth the look of fine lines

Accelerated Retinol SA is a unique combination of the following ingredients:

Retinol SA

Exclusive sustained action works to continuously renew the look of skin throughout the day, helping to smooth wrinkles fast and diminish the look of dark spots. Retinol SA is scientifically superior to other forms of Vitamin A, such as Pro-Retinol and Retinol Palmitate, in its ability to prove benefit.

Glucose Complex

A Retinol SA booster that accelerates skin’s surface activity for rapid results on appearance of fine line and wrinkles.

Hyaluronic Acid

Adds line plumping moisture to help hydrate, replenish and rejuvenate the look of skin.

Gentle enough for daily use.

  • Allergy tested
  • Oil-free
  • Non-comedogenic


Apply twice daily to cleansed face and neck. Smooth a pearl-sized amount evenly in gentle massaging strokes until fully absorbed. Replace and tighten cap when not in use.


While Neutrogena® strives to keep ingredient lists on this website as accurate as possible, we cannot guarantee that these lists are complete, reliable, up-to-date, and error-free. Please refer to the ingredients list on the product packaging for the most accurate list of ingredients.

Water, Pentaerythrityl Tetraethylhexanoate, Glycerin, Dimethicone, PPG-15 Stearyl Ether, Stearyl Alcohol, Cetearyl Alcohol, Butylene Glycol, Glyceryl Behenate, Ceteareth-20, Isohexadecane, Cyclopentasiloxane, Dimethicone Crosspolymer, Polyethylene, Sodium Polyacrylate, Phenoxyethanol, Caprylyl Glycol, Sodium Acryloyldimethyltaurate/VP Crosspolymer, Polyacrylamide, Fragrance, C13-14 Isoparaffin, PTFE, Chlorphenesin, Polysorbate 20, Hydrolyzed Myrtus Communis Leaf Extract, Retinol, BHT, Sodium Hyaluronate, Disodium EDTA, Laureth-7, Sodium Hydroxide, Ascorbic Acid.

When I first heard of this product I thought give it a go, you never know. I have been using this now for maybe 3 months or so and I have definitely seen a reduction in wrinkles around my eyes. I will continue using it for sure.
Rated 5 out of 5 by from Unexpected results halt mini science project I hate buying things that promise but do not deliver, so I redid a favorite experiment. The plan was to treat the R side of my face with this cream and perform my normal routine on the L side. For a week, because that was the advertising promise I have never had a cream or serum or balm pass this test, since both sides of my face have looked the same at the end of the test. This time, I stopped the test after two days, the improvement was so obvious. What a wonderful surprise. My lips are plumped up, my deep wrinkles are flattening out, my smaller wrinkles are disappearing. Bravo! This is AWESOME!
Date published: 2017-03-05
Rated 5 out of 5 by from My Miracle a jar! I have been using Neutrogena products off and on since my 20's, but since I have gotten older I seem to always turn to Neutrogena products first. I have made many mistakes of buying a higher end price product thinking it was going to be better for my skin, but I have learned the hard way. The Rapid Wrinkle Repair - Regenerating Cream is hands down the best I have used. I am on my second jar and my skin keeps looking better and wrinkles have been disappearing, also any sun spots I had from last years tan are disappearing, and my skin looks fabulous. My skin care line is Neutrogena all the way, I have stopped spenidng money on higher priced ineffective products!
Date published: 2018-01-16
Rated 3 out of 5 by from Not as good as advertised. I waited to write a review because I had just bought it not too long ago. I was using a different product which was excellent for my laugh lines and forehead lines which was great but my daughter said she got your product and it was really good. She is a lot younger than me and I don't feel it is doing as well as she said it did for her. I used it night and day and it did dry out my skin on my laugh lines around my eyes. It didn't erase what my previous product did on my laugh lines around my mouth which is good. I stopped using it around the areas where it dried my skin out. I will not buy this again but I will finish the product.
Date published: 2018-03-10
Rated 5 out of 5 by from Moistures and reduces wrinkles Neutrogena I'm 42 and have crows feet and smile lines. I've been using Neutrogena Rapid Winkle Repair Regenerating Cream for two weeks, having worked my way up to using it twice daily most days, applying it to both my face and neck. Applying the cold rich cream feels good every time. Since I have combo skin and the cream moisturizes my skin very well, I don't use it every morning. I appreciate how it's not greasy and almost fragrance-free, and it has never irritated my skin. In under a week, my crows feet weren't visible, and my smile lines weren't as deep. My skin feels and looks smooth, and the redness I normally have near my nose even disappeared. I thank PINCHme for the free sample! I love this product and would recommend it to anyone looking to reduce wrinkles.
Date published: 2017-02-12
Rated 1 out of 5 by from Burning, redness, and swelling around eyes I bought this cream about 5 days ago. I loved the softness of it on my skin and the smell is pleasant. On day 2 of using it, I noticed some tingling but nothing concerning. By day 3, my face actually hurt to touch it. It is red and I cannot put anything on it without it burning. Last night I noticed all around my eyes are swollen, my wrinkles are now more noticeable and I look so much older. I wish I had read previous reviews which stating similar results. I haven't used the product in two days and my face is still red, swollen, and painful. Thinking of going to see a dermatologist to see what can be done about the burning, tingling, painful sensation that won't go away. I look awful.
Date published: 2019-01-22
Rated 5 out of 5 by from Wrinkles gone on forehead This cream makes my skin feel luxurious and thoroughly moisturized. My dentist thought I had gotten Botox on my forehead as I had no wrinkles. I am 50. This cream miraculously faded the large deep wrinkles I had there, which I never expected a cream could do. I've actually never seen results with any cream before and I have previously paid for high end products such as Revive. I have been using the serum with it the last couple of weeks and that has helped also. I really can't believe it has dramatically diminished my forehead wrinkles. Hope it helps you!
Date published: 2019-05-07
Rated 5 out of 5 by from Best skin and wrinkle cream I have ever used! I began using this twice a day about 2 weeks ago. I do use more than "a pearl-sized drop" even though I have very sensitive skin. After washing my face every night with Neutrogena soap, which I have been using all my life (I'm 65) and with a Neutrogena facial brush 2-3 times a week, I use this cream both before bedtime and before putting on my make-up in the mornings. My skin is so smooth and bright and less wrinkled that my husband even mentioned it! I hope Neutrogena never changes the ingredients here! It is fantastic! Try it yourself!
Date published: 2017-04-04
Rated 5 out of 5 by from Wait a week (as promised) I nearly gave up on this cream on day 3, I hadn’t used a retinol product before and didn’t know anything about the ingredient and hadn’t heard of the “retinoid uglies”. My skin felt soft but looked terrible- red, angry, wrinkled and sore. I had over applied the product thinking more is best- rookies mistake. A week in and the results started to show, I’d done some research, stuck with the recommended amount, avoided my eyelids(!) and my skin was adjusting. So glad I stayed with it as the benefits are amazing and I am already getting compliments and noticing a massive difference in wrinkles and skin tone. I have a glow again that I thought was gone.
Date published: 2020-11-03
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